Ecotoxicogenomics for biomarkers of exposure to pollutants in the aquatic indicator species, Daphnia magna
In order to implement the most advanced practices for ensuring water quality, rapid and accurate screens are necessary to predict the environmental toxicity of manufacturing or agriculture chemicals.gene expression signatures We are developing genomic methods that will allow for rapid assessment of water quality and aquatic environmental toxicity using gene expression signatures in the model organism Daphnia magna.
Development of biosensors for munitions compound based on signature gene expression of fathead minnow, Pimephales promelas
The objective of this project is to identify gene biomarkers of exposure to munitions constituents (MCs) and gene markers indicative of toxic mode of action in the organism, Fathead minnow, Pimephales promelas. The gene biomarkers are examined for their ability to identify and quantitate levels of different MCs in groundwater. Assays will also be examined for ability to discriminate between toxic stress due to non-target pollutants (e.g. agrochemicals, bacterial degradation products of MCs, or petrochemicals) and target MCs.